Researchers Lin et al at Taipei Medical University shared an alarming finding that blue light, similar to that emitted by smart phones, can lead to retinal disruption in rats. They used the Phoenix-Micron’s Phoenix MICRON® fundus camera and the image-guided OCT to demonstrate blood vessel leakage and retinal thinning after intermittent blue light exposure. Lin
11.07
2018
Phoenix’s anterior chamber OCT evaluates corneal wound healing in guinea pigs
McDaniels et al at the US Army Institute of Surgical Research used the Phoenix anterior chamber OCT to evaluate the safety of an ocular wound chamber after a corneal injury in guinea pigs. The research group developed an ocular wound chamber that encases the eye and allows for controlled delivery of therapeutics and eye lubricant.
12.06
2018
Phoenix OCT reveals detailed images of retinal and anterior chamber infiltrates in a uveitis mouse model
In their article “Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model,” Chu et al used images captured with the Phoenix OCT of the retina and anterior segment to correlate infiltrate level with neutrophil count during uveitis. To develop objective multimodal methods of analyzing infected eyes, they also examined flow cytometry of infiltrates,
13.03
2018
Micron IV Fundus Images Reveal Recapitulation of Phenotype in Retinal Dystrophy
Butterfly-shaped pigment dystrophy is an eye disease that produces butterfly-shaped lesions near the macula which can result in diminished visual acuity. In an article published in Nature Genetics, Saksens, Krebs, et al linked a mutation in the CTNNA1 gene to the disease in three families and found a mouse with the same mutation that showed a similar phenotype to the humans. The Micron IV rodent fundus camera revealed retinal dystrophy similar to humans.
19.02
2018
Surprising Preservation of Cone Function in Aged Alzheimer's-model Mice
Researchers at the University of Laval in Québec, Canada discovered unexpected findings with the Phoenix full field Ganzfeld electroretinography (ERG) system studying Alzheimer’s model mice. ERG assesses the function of the retinal cells including the photoreceptors, bipolar cells, and amacrine cells by flashing light at the retina and recording the electrical responses of the cells. By examining the height and speed of the electrical response wave forms, the retinal function integrity can be measured. The Phoenix Ganzfeld ERG system flashes green or UV light on the entire retina, which can tease out the function of rods, M-cones, and S-cones separately.
16.01
2018
Using the MICRON® IV to Study Light Induced Retinal Degeneration
Dr. Rafael Ufret-Vincenty’s lab at University of Texas Southwestern Medical Center has developed a novel model for light damage using the Micron IV rodent retinal imaging camera. This quick and consistent light damage model leads to fundus abnormalities and retinal thinning as measured by the Micron image-guided OCT and semi-automated layer analysis tool, Insight. In two elegant articles, the researchers provided proof of concept in pigmented mice, which are a better model for human eye light damage than overly sensitive albino mice, which demonstrated bleached fundus and outer retinal layer thinning.