Researchers at Henan Province Eye Hospital in China have made great strides in studying endotoxin-induced uveitis (EIU) by creating a novel EIU model in zebrafish. Uveitis is an ocular inflammation and one of the main causes of visual impairment, accounting for 10-15% of global blindness. Mice have typically been the research animal of choice however
19.01
2022
Deep learning provides unbiased evaluation of uveitis severity levels in 1500 Phoenix MICRON® mouse fundus images
In 2020, researchers Jian Sun, Xiaoqin Huang et al, in the Laboratory of Immunology at the National Eye Institute, confirmed in the lab what has been going on in human ophthalmology in recent years, but with a twist. Their deep learning model enabled identification of retinal disease stages with noteworthy accuracy. What marked their work
17.07
2019
Using the Phoenix MICRON® IV to examine a potential treatment for disrupted retinal vasculature
Many eye diseases, including age-related macular degeneration, diabetic macular edema, cancer growth, and uveitis, involve disrupted blood vessel growth and leakage. Curing the leakage and growth helps modulate and treat the underlying disease. The Phoenix MICRON® IV fundus camera allows for clear visualization of the rodent vasculature in bright field and with fluorescein angiography. Mirando
12.06
2018
Phoenix OCT reveals detailed images of retinal and anterior chamber infiltrates in a uveitis mouse model
In their article “Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model,” Chu et al used images captured with the Phoenix OCT of the retina and anterior segment to correlate infiltrate level with neutrophil count during uveitis. To develop objective multimodal methods of analyzing infected eyes, they also examined flow cytometry of infiltrates,