Our latest blog post veers from the traditional focus on a singular research paper to bring you an enthralling narrative at the crossroads of progressive inherited retinal dystrophy (IRD), the frigid expanses of Antarctica, marathon endurance, the expressive world of art, and the transformative realm of retinal research. This story encompasses gene editing, animal models,
16.08
2023
Small zebrafish are impressive, effective models for studying endotoxin induced uveitis
Researchers at Henan Province Eye Hospital in China have made great strides in studying endotoxin-induced uveitis (EIU) by creating a novel EIU model in zebrafish. Uveitis is an ocular inflammation and one of the main causes of visual impairment, accounting for 10-15% of global blindness. Mice have typically been the research animal of choice however
11.07
2023
Researchers find early signs of Alzheimer’s disease (AD) in the mouse retina and develop a non-invasive artificial intelligence-based system that could be used to diagnose the disease before the appearance of clinical symptoms
Progress in diagnosing and treating Alzheimer’s disease (AD) has been accelerating over the last few years. Until now, AD has been difficult to diagnose. The disease can be present years before distinguishable symptoms manifest. Non-invasive diagnostic tests have been lacking, and diagnosis often relies on memory, cognitive, and behavioral tests. In 2011, Koronyo-Hamaoui M, Koronyo
08.03
2023
Researchers at the University of Copenhagen demonstrate for the first time that diet induced obesity (DIO) leads to raised intracranial pressure (ICP) and subsequent clinically relevant symptom development.
In the paper “The impact of obesity‑related raised intracranial pressure in rodents” published in Scientific Reports journal, Westgate and collaborators used the Phoenix MICRON® image-guided OCT system, along with the Phoenix MICRON® Insight software, in the measurement of the retinal anatomical changes caused by intracranial hypertension in obese rats. The Problem: Intracranial pressure (ICP) measures the
13.10
2022
Where do research ideas come from?
Where do research ideas come from? Do they arrive in a thunderbolt eureka moment, or do they start as an observation or hunch, requiring some time to simmer, brew, incubate and grow? Some may evolve from an accidental or serendipitous discovery during a routine process. Observant operators of the Phoenix MICRON® retinal imaging system may
28.02
2022
Analysis of imaging, structure and function using Phoenix MICRON™ modalities expand the understanding of ocular features of Down Syndrome in mouse models
In their paper “Quantitative Analysis of Retinal Structure and Function in Two Chromosomally Altered Mouse Models of Down Syndrome”, researchers Victorino, Scott-McKean, et al leveraged the multi-modality capabilities of the Phoenix MICRON™ retinal imaging platform, to produce an image-rich research paper looking at the ocular features of Down Syndrome in two mouse models; Ts65Dn and