2024

Newly Discovered Eye-Brain Immune Connection Opens Doors for Novel Therapies

Researchers at Yale University have uncovered a previously unknown lymphatic drainage system connecting the back of the eye to the brain, potentially revolutionizing our understanding of eye-brain immunity and opening new avenues for treating central nervous system diseases. By studying the immune response to herpes simplex virus in the brain, the team led by Dr.

2023

Exploring the Intersection of Art and Retinal Research: A Journey of Discovery

Our latest blog post veers from the traditional focus on a singular research paper to bring you an enthralling narrative at the crossroads of progressive inherited retinal dystrophy (IRD), the frigid expanses of Antarctica, marathon endurance, the expressive world of art, and the transformative realm of retinal research. This story encompasses gene editing, animal models,

2023

Small zebrafish are impressive, effective models for studying endotoxin induced uveitis

Researchers at Henan Province Eye Hospital in China have made great strides in studying endotoxin-induced uveitis (EIU) by creating a novel EIU model in zebrafish.  Uveitis is an ocular inflammation and one of the main causes of visual impairment, accounting for 10-15% of global blindness.  Mice have typically been the research animal of choice however

2023

Researchers find early signs of Alzheimer’s disease (AD) in the mouse retina and develop a non-invasive artificial intelligence-based system that could be used to diagnose the disease before the appearance of clinical symptoms

Progress in diagnosing and treating Alzheimer’s disease (AD) has been accelerating over the last few years. Until now, AD has been difficult to diagnose. The disease can be present years before distinguishable symptoms manifest. Non-invasive diagnostic tests have been lacking, and diagnosis often relies on memory, cognitive, and behavioral tests. In 2011, Koronyo-Hamaoui M, Koronyo

2023

Researchers at the University of Copenhagen demonstrate for the first time that diet induced obesity (DIO) leads to raised intracranial pressure (ICP) and subsequent clinically relevant symptom development.

In the paper “The impact of obesity‑related raised intracranial pressure in rodents” published in Scientific Reports journal, Westgate and collaborators used the Phoenix MICRON® image-guided OCT system, along with the Phoenix MICRON® Insight software, in the measurement of the retinal anatomical changes caused by intracranial hypertension in obese rats. The Problem: Intracranial pressure (ICP) measures the

2022

Where do research ideas come from?

Where do research ideas come from?  Do they arrive in a thunderbolt eureka moment, or do they start as an observation or hunch, requiring some time to simmer, brew, incubate and grow?  Some may evolve from an accidental or serendipitous discovery during a routine process. Observant operators of the Phoenix MICRON® retinal imaging system may

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