2020

Targeting VEGF164 in Müller cells may be useful to treat retinopathy of prematurity

In Nature’s Scientific Reports, Becker et al use the Phoenix MICRON® IV, OCT, and focal ERG to assess the therapeutic value of knocking down a splice variant of VEGF in Müller cells in a model of Retinopathy of Prematurity (ROP). ROP is characterized by delayed vascularization of the retina after disrupted oxygen levels, followed by […]

2020

Imaging unanesthetized mice with the Phoenix MICRON® OCT provides consistent retinal degeneration measurements

In the recently published review, “Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss,” researchers from The Jackson Laboratory in Bar Harbor, Maine and Mahidol University in Bangkok, Thailand performed an extensive literature search to find mouse models of single-gene mutations leading to photoreceptor loss and retinal degeneration. Using the Phoenix MICRON® III and […]

2020

Retina as window to the brain: Stunning Phoenix MICRON® fluorescein angiography images of brain and retinal vasculature

Novel comparison of retina and brain vasculature leads to stunning Phoenix MICRON® images of fluorescent brain blood vessels The Phoenix MICRON® imaging platform produces stunning images of fluorescent retinal vasculature through fluorescein angiography but for the first time, researchers have also captured beautiful images of cortical brain vasculature. Hui et al, in their well-written and […]

2020

Measuring adeno-associated virus improvements with Phoenix MICRON® fluorescent imaging and Phoenix MICRON® Ganzfeld ERG

A team of researchers at the Indian Institutes of Technology have published three detailed articles examining how to improve adeno-associated viruses (AAV). Maurya, S, Mary, B, Jayandharan, GR et al -approach the improvement of the viruses in a stunningly detailed gene-to-cell-to-whole-mouse model, narrowing down a multitude of options and producing impressive fluorescent fundus images and […]

2019

Treating retinitis pigmentosa with cassia seed: Retinal layer analysis with the Phoenix MICRON OCT and Insight software

Retinitis pigmentosa is a genetic disorder that leads to severe vision impairment and blindness. The photoreceptors die off in a self-propelling cycle of rod and cone dysfunction, leading to glial activation and death, leading to more dysfunction. There are a few experimental treatments but no widespread effective treatment or cure. Cassia seed is used in […]

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