Diabetic retinopathy is a crippling complication of diabetes that can lead to loss of vision, characterized by retinal inflammation, neurodegeneration, and disorganized microvascularization . Oxidative stress is crucial to the development of diabetic retinopathy. Iron is an essential micronutrient but, in excess, can become a highly damaging oxidative species. Excessive iron has been implicated in Parkinson’s
20.09
2019
Phoenix MICRON® OCT tracks individual stem cells in the rat retina
In the July edition of Nanomedicine journal, Chemla et al demonstrate a fascinating and novel way to label and track individual photoreceptor precursor cells migrating within the retina with fluorescence and gold nanoparticle tagging using the Phoenix MICRON® and OCT. Many retinal diseases such as age-related macular degeneration and retinitis pigmentosa are characterized by photoreceptor
26.08
2019
The Secret to a Perfect Fundus Image
Hint: It Starts with the Animal Angle During our hands-on training, we review animal positioning until every user is completely comfortable. But like most other lab equipment task, it does take some practice. Aligning the animal just right can be the difference between a great and a good fundus image. We’ve put together a
17.07
2019
Using the Phoenix MICRON® IV to examine a potential treatment for disrupted retinal vasculature
Many eye diseases, including age-related macular degeneration, diabetic macular edema, cancer growth, and uveitis, involve disrupted blood vessel growth and leakage. Curing the leakage and growth helps modulate and treat the underlying disease. The Phoenix MICRON® IV fundus camera allows for clear visualization of the rodent vasculature in bright field and with fluorescein angiography. Mirando
19.06
2019
Developing a unique, novel dry AMD model with the Phoenix MICRON® laser injector
The most common cause of blindness in developed societies, age-related macular degeneration (AMD) robs the victim of the crucially important focused macular vision. While still devastating, wet AMD has a robust mouse model and the treatment option of anti-vascular endothelial growth factor (VEGF) subretinal injections. The Phoenix MICRON® laser allows precise delivery of 532 nm
14.05
2019
ARVO 2019: Frogs, Glue and CNV
Another ARVO passed by in a blur of research, scientific discussions, and seeing science friends. If you came by our booth, thank you for swinging by to chat with the Phoenix team. If you didn’t get a chance, please let me know if you have any questions about the Micron system and look for our