In their paper, “Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy,” Askou et al develop an adeno-associated virus (AAV) treatment for age-related macular degeneration. Beautiful fluorescent fundoscopy performed with the Phoenix MICRON® validated the success of the subretinal AAV injection, while precise choroidal neovascularization (CNV) induced by Phoenix laser burns confirmed that the
15.02
2019
Corneal Thickness Analysis using OCT
Corneal images taken with the Phoenix Micron IV OCT used for thickness analysis King et al, a consortium of researchers at a range of institutions, recently used the Phoenix Micron IV OCT to examine corneal thickness in their article, “Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing
16.11
2018
Fundus and OCT imaging shows that smart phone-like blue light exposure leads to retinal disruption in rats
Researchers Lin et al at Taipei Medical University shared an alarming finding that blue light, similar to that emitted by smart phones, can lead to retinal disruption in rats. They used the Phoenix-Micron’s Phoenix MICRON® fundus camera and the image-guided OCT to demonstrate blood vessel leakage and retinal thinning after intermittent blue light exposure. Lin
11.07
2018
Phoenix’s anterior chamber OCT evaluates corneal wound healing in guinea pigs
McDaniels et al at the US Army Institute of Surgical Research used the Phoenix anterior chamber OCT to evaluate the safety of an ocular wound chamber after a corneal injury in guinea pigs. The research group developed an ocular wound chamber that encases the eye and allows for controlled delivery of therapeutics and eye lubricant.
12.06
2018
Phoenix OCT reveals detailed images of retinal and anterior chamber infiltrates in a uveitis mouse model
In their article “Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model,” Chu et al used images captured with the Phoenix OCT of the retina and anterior segment to correlate infiltrate level with neutrophil count during uveitis. To develop objective multimodal methods of analyzing infected eyes, they also examined flow cytometry of infiltrates,
13.03
2018
Micron IV Fundus Images Reveal Recapitulation of Phenotype in Retinal Dystrophy
Butterfly-shaped pigment dystrophy is an eye disease that produces butterfly-shaped lesions near the macula which can result in diminished visual acuity. In an article published in Nature Genetics, Saksens, Krebs, et al linked a mutation in the CTNNA1 gene to the disease in three families and found a mouse with the same mutation that showed a similar phenotype to the humans. The Micron IV rodent fundus camera revealed retinal dystrophy similar to humans.