In the recently published review, “Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss,” researchers from The Jackson Laboratory in Bar Harbor, Maine and Mahidol University in Bangkok, Thailand performed an extensive literature search to find mouse models of single-gene mutations leading to photoreceptor loss and retinal degeneration. Using the Phoenix MICRON® III and
09.11
2019
Treating retinitis pigmentosa with cassia seed: Retinal layer analysis with the Phoenix MICRON OCT and Insight software
Retinitis pigmentosa is a genetic disorder that leads to severe vision impairment and blindness. The photoreceptors die off in a self-propelling cycle of rod and cone dysfunction, leading to glial activation and death, leading to more dysfunction. There are a few experimental treatments but no widespread effective treatment or cure. Cassia seed is used in
20.09
2019
Phoenix MICRON® OCT tracks individual stem cells in the rat retina
In the July edition of Nanomedicine journal, Chemla et al demonstrate a fascinating and novel way to label and track individual photoreceptor precursor cells migrating within the retina with fluorescence and gold nanoparticle tagging using the Phoenix MICRON® and OCT. Many retinal diseases such as age-related macular degeneration and retinitis pigmentosa are characterized by photoreceptor
26.08
2019
The Secret to a Perfect Fundus Image
Hint: It Starts with the Animal Angle During our hands-on training, we review animal positioning until every user is completely comfortable. But like most other lab equipment task, it does take some practice. Aligning the animal just right can be the difference between a great and a good fundus image. We’ve put together a
14.05
2019
ARVO 2019: Frogs, Glue and CNV
Another ARVO passed by in a blur of research, scientific discussions, and seeing science friends. If you came by our booth, thank you for swinging by to chat with the Phoenix team. If you didn’t get a chance, please let me know if you have any questions about the Micron system and look for our
27.03
2019
Phoenix MICRON® CNV System used to test a novel treatment for age-related macular degeneration
In their paper, “Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy,” Askou et al develop an adeno-associated virus (AAV) treatment for age-related macular degeneration. Beautiful fluorescent fundoscopy performed with the Phoenix MICRON® validated the success of the subretinal AAV injection, while precise choroidal neovascularization (CNV) induced by Phoenix laser burns confirmed that the