2023

Researchers find early signs of Alzheimer’s disease (AD) in the mouse retina and develop a non-invasive artificial intelligence-based system that could be used to diagnose the disease before the appearance of clinical symptoms

Progress in diagnosing and treating Alzheimer’s disease (AD) has been accelerating over the last few years. Until now, AD has been difficult to diagnose. The disease can be present years before distinguishable symptoms manifest. Non-invasive diagnostic tests have been lacking, and diagnosis often relies on memory, cognitive, and behavioral tests. In 2011, Koronyo-Hamaoui M, Koronyo

2023

Researchers at the University of Copenhagen demonstrate for the first time that diet induced obesity (DIO) leads to raised intracranial pressure (ICP) and subsequent clinically relevant symptom development.

In the paper “The impact of obesity‑related raised intracranial pressure in rodents” published in Scientific Reports journal, Westgate and collaborators used the Phoenix MICRON® image-guided OCT system, along with the Phoenix MICRON® Insight software, in the measurement of the retinal anatomical changes caused by intracranial hypertension in obese rats. The Problem: Intracranial pressure (ICP) measures the

2021

Subretinal injection damage has implication for experimental control and treatment in rat model of retinopathy of prematurity

In their 2017 article, “Effect of subretinal injection on retinal structure and function in a rat oxygen-induced retinopathy model,” Becker et al used the Phoenix MICRON® IV fundus camera, Phoenix MICRON® OCT2 and corresponding layer analysis software Insight 2D, and the Phoenix MICRON® focal ERG to find that subretinal injection of saline or even introduction