For astronauts gazing out at the vastness of space, their eyes are not just windows to the cosmos but sensitive and vital instruments that must endure the challenging environment of life beyond Earth’s atmosphere. Although pressure suits, capsules, and space stations provide critical protection, astronauts are constantly exposed to extraterrestrial forces that impact various organ
17.07
2019
Using the Phoenix MICRON® IV to examine a potential treatment for disrupted retinal vasculature
Many eye diseases, including age-related macular degeneration, diabetic macular edema, cancer growth, and uveitis, involve disrupted blood vessel growth and leakage. Curing the leakage and growth helps modulate and treat the underlying disease. The Phoenix MICRON® IV fundus camera allows for clear visualization of the rodent vasculature in bright field and with fluorescein angiography. Mirando
19.06
2019
Developing a unique, novel dry AMD model with the Phoenix MICRON® laser injector
The most common cause of blindness in developed societies, age-related macular degeneration (AMD) robs the victim of the crucially important focused macular vision. While still devastating, wet AMD has a robust mouse model and the treatment option of anti-vascular endothelial growth factor (VEGF) subretinal injections. The Phoenix MICRON® laser allows precise delivery of 532 nm
27.03
2019
Phoenix MICRON® CNV System used to test a novel treatment for age-related macular degeneration
In their paper, “Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy,” Askou et al develop an adeno-associated virus (AAV) treatment for age-related macular degeneration. Beautiful fluorescent fundoscopy performed with the Phoenix MICRON® validated the success of the subretinal AAV injection, while precise choroidal neovascularization (CNV) induced by Phoenix laser burns confirmed that the