{"id":1848,"date":"2017-08-15T00:36:10","date_gmt":"2017-08-15T00:36:10","guid":{"rendered":"http:\/\/www.phoenixreslabs.com\/?p=1848"},"modified":"2026-04-02T17:51:28","modified_gmt":"2026-04-02T17:51:28","slug":"glaucoma-fluorescent-imaging","status":"publish","type":"post","link":"https:\/\/phoenixmicron.com\/es\/glaucoma-fluorescent-imaging\/","title":{"rendered":"Studying Glaucoma with Micron IV Fluorescent RGC Imaging"},"content":{"rendered":"<figure id=\"attachment_1851\" aria-describedby=\"caption-attachment-1851\" style=\"width: 350px\" class=\"wp-caption alignnone\"><img decoding=\"async\" class=\"size-full wp-image-1849 lazyload\" data-src=\"https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_10-26-53-93.png\" alt=\"Micron IV glaucoma\" width=\"350\" height=\"350\" data-srcset=\"https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_10-26-53-93.png 400w, https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_10-26-53-93-150x150.png 150w, https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_10-26-53-93-300x300.png 300w\" data-sizes=\"(max-width: 350px) 100vw, 350px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 350px; --smush-placeholder-aspect-ratio: 350\/350;\" \/><figcaption id=\"caption-attachment-1851\" class=\"wp-caption-text\">The brightest yellow fluorescent protein-tagged RGC are evident in the bright field image shown.<\/figcaption><\/figure>\n<figure id=\"attachment_1851\" aria-describedby=\"caption-attachment-1851\" style=\"width: 350px\" class=\"wp-caption alignnone\"><img decoding=\"async\" class=\"size-full wp-image-1851 lazyload\" data-src=\"https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_09-21-26-41.png\" alt=\"Protein-tagged mural cells\" width=\"350\" height=\"350\" data-srcset=\"https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_09-21-26-41.png 400w, https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_09-21-26-41-150x150.png 150w, https:\/\/phoenixmicron.com\/wp-content\/uploads\/2017\/10\/2017-06-26_09-21-26-41-300x300.png 300w\" data-sizes=\"(max-width: 350px) 100vw, 350px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 350px; --smush-placeholder-aspect-ratio: 350\/350;\" \/><figcaption id=\"caption-attachment-1851\" class=\"wp-caption-text\">A second genetically modified mouse has rd fluorescent protein-tagged mural cells that surround the vasculature in the retina seen under fluorescent filters<\/figcaption><\/figure>\n<p>The Di Polo lab at the University of Montreal researches glaucoma using the Micron IV rodent retinal imaging camera and OCT module. Their scientists captured stunning fluorescent images with the Micron IV of mice genetically modified to produce yellow fluorescent protein (YFP)-tagged retinal ganglion cells (RGC). the brightest RGC are visible in the bright field image along with blood vessels, optic nerve, and the retinal surface. In the fluorescent image, the RGC are highlighted and their dendritic processes, appearing as thin lines emanating from the central cell body, are clearly visible. Scientists also examined mice with red fluorescent protein (RFP)-tagged mural cells with the Micron IV; the mural cells clearly highlighted surrounding the vasculature in the fluorescent image.<\/p>\n<p>The Di Polo lab studies the effect of glaucoma on retinal ganglion cells, working toward a treatment to prevent neuronal cell death. The Micron IV will aid in their glaucoma research by allowing them to observe RGC over time as the disease progresses. Using geographic markers on the retina, the same RGC can be monitored longitudinally, especially with simple switching of filters from bright field to fluorescent while the mouse stays in the same position. They will also use the OCT to observe the irido-corneal angle over time.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dendrites may be retracted in several diseases as glaucoma. Studying morphology of dendritic arbors may give us an idea about functional deficits in those diseases. The Di Polo lab at the University of Montreal researches glaucoma using the Micron IV rodent retinal imaging camera and OCT module. Their scientists captured stunning fluorescent images with the Micron IV of mice genetically modified to produce yellow fluorescent protein (YFP)-taged retinal ganglion cells (RGC). the brightest RGC are visible in the bright field image along with blood vessels, optic nerve, and the retinal surface.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[330],"tags":[366,923],"class_list":["post-1848","post","type-post","status-publish","format-standard","hentry","category-micron-iv","tag-glaucoma","tag-celulas-ganglionares-de-la-retina-cgr"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Studying Glaucoma with Micron IV Fluorescent RGC Imaging - Phoenix-micron<\/title>\n<meta name=\"description\" content=\"Dendrites may be retracted in several diseases as glaucoma. Studying morphology of dendritic arbors may give us an idea about functional deficits.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/phoenixmicron.com\/es\/glaucoma-fluorescent-imaging\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Studying Glaucoma with Micron IV Fluorescent RGC Imaging - Phoenix-micron\" \/>\n<meta property=\"og:description\" content=\"Dendrites may be retracted in several diseases as glaucoma. 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